Rheumatoid Arthritis Sample Essay Assignment Paper
Rheumatoid Arthritis Sample Essay Assignment Paper
The term “rheumatoid arthritis” (RA) was first proposed by A.B. Garrod in 1858 (Wyngaarde, JB. 1992). It is a chronic, systemic, inflammatory disease predominantly affecting freely movable joints and frequently a variety of organs. Rheumatoid arthritis affects the joints because of the essential role of the synovium in regulating inflammation (Lipsky PE, 2007).
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RA occurs worldwide in all ethnics groups. The peak incidence of onset is between the 4th and 6th decade, but may begin at any time from childhood to later life. It affects up to 1% of the world’s population and is associated with significant morbidity and mortality (Buch M, 2002). Anthropologic evidence of RA has been found in the New World, but not the Old World skeletons proposing, but no proven that an etiologic agent was carried to Europe by explorers of the Americas. Females are 2-4 times more likely to be affected than males (Koopman WJ, 2001). Nothing was known about RA before the early 19th century. And to this date, the etiology of RA is unclear, and there exists no known specific diagnostic test for it.
