Review ML’s new diagnosis and potential treatment options Essay Assignment Paper

Review ML’s new diagnosis and potential treatment options Essay Assignment Paper

Review ML’s new diagnosis and potential treatment options Essay Assignment Paper

Pharmacology CASE STUDY

Respond to the following post in two different replies. Your responses should be in a well-developed paragraph (300-350 words) to each peer. Integrating an evidence-based resource that is different than the one you used for the initial post.

Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.

APA format,  Cites three or more references, using at least one new scholarly resource .

1st POST ( PLEASE RESPOND)

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The purpose of this discussion post is to review ML’s new diagnosis and potential treatment options. For ML, her new diagnosis of stage A heart failure does not mean she has any structural abnormality with her heart. The pathophysiology of this condition includes the fact that ML has preexisting conditions that increase her risk of developing heart failure in the future, if left untreated. The conditions that would cause ML to be diagnosed with stage A heart failure and potentially lead to further heart failure staging if left untreated include hypertension, coronary artery disease, or diabetes mellitus (Woo & Robinson, 2020). The main goal with stage A heart failure includes managing comorbidities to prevent heart failure development (Tanaka, 2018). The main goal of this belongs with consistent blood pressure management.

For ML, the main goal in her treatment therapy will include good blood pressure control. According to Woo and Robinson (2020), ACE inhibitors are typically the first line of treatment, as research has displayed these medications to improve patient symptoms, decrease mortality, and increase life expectancy. As these medications are typically shown to reduce the mechanisms that lead to heart failure, this would be the recommended drug of choice for ML to prevent her progression of stage A heart failure. Due to the fact that digoxin has not been shown to present a mortality benefit, although it may improve quality of life in patients with congestive heart failure, this would not be the first choice of treatment for ML. If, however, this was chosen for ML to treat her stage A heart failure and she was experiencing halos, this would be a sign of digoxin toxicity (Cummings & Swoboda, 2020). If ML has any renal impairment, she would be at increased risk for developing digoxin toxicity. To evaluate for toxicity, a random digoxin level should be checked as well as confirming when the last dose was taken by ML. Once an EKG and basic lab values are obtained, Digibind is an antidote that will assist with eliminating the toxicity, especially in life-threatening instances (Cummings & Swoboda, 2020).

If digoxin is chosen to be the treatment for ML, special consideration should be taken if ML is an older adult or has renal impairment (Woo & Robinson, 2020). Along with this, digoxin was associated with increased risk of death and worsening heart failure in women compared to men (Jackson, 2015). Due to these risks and potential complications, ACE inhibitors will remain to be the drug class of choice for ML. Due to the risk of hypotension, a low-dose ACE inhibitor should be initiated, with a gradual increase in dose occurring to improve exercise tolerance and to relieve any potential symptoms. While doing this, BP and renal function should be closely monitored. Along with this, due to the risk of increased potassium levels, serum electrolyte levels should be regularly monitored. Lastly, one potential side effect that is typically the primary cause for discontinuation amongst patients is the risk of a persistent dry cough (Woo & Robinson, 2020). Ideally, with proper treatment and close monitoring, ML’s stage A heart failure will not progress to additional stages.

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