Nursing Challenges of Antibacterial Resistance Essay Assignment Paper
Nursing Challenges of Antibacterial Resistance Essay Assignment Paper
The discovery of anti-microbial led to an optimism of curbing many health issues. But, owing to its use, misuse, over-exploitation it has resulted into microorganism with one or more than antimicrobial resistance. Drug resistance has no boundaries and emerging as a pandemic globally raising the concern of health authorities. The current essay gives a brief idea causes, challenges, and responses to different types of Antimicrobial resistance occurring worldwide.
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CAUSES
Antimicrobial resistance is not a new concept. Going back through pages of history, it can be known Streptococcus pyrogenes was the first micro-organism to get anti-microbial resistance isolated from military hospitals in the 1930’s. Since the list never halted with the addition of a new strain either in single drug-resistant or multi-drug resistant category. This has led to a number of clinical issues over the years. From a mechanism point of view, it is only when antimicrobial or antibiotic and antimicrobial drug resistance determines in an organism present in an environment simultaneously, it leads to antimicrobial drug resistance.
Through specific antimicrobial resistance genes, these micro-organisms propagate beyond their original host and geographical boundaries leading to this pandemic. A number of mobile genetic elements such as naked DNA, plasmid, transposons, and bacteriophages can help in transferring the resistance gene from one organism to other irrespective of species and strain. The genes which are transferred either bears single anti-microbial resistance target or multi-drug resistance through multiple accumulations of resistance genes. Antimicrobial resistance mechanisms have also gone a number of evolutions making it tough for clinicians and researchers to address the problem. In absence of mentioned mobile genetic elements mutations accumulated in particular chromosomes over the period can give rise to resistance. Similarly, a mutation in target enzymes can also lead to mutations observed in E.coli strains resistance against floroquinolones.Nursing Challenges of Antibacterial Resistance
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