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Case Study: Cardiovascular System – Atherosclerosis essay assignment
Hematologic System
Case Study: Pernicious Anemia
approx 30 min
Mr. Alvis, age 57, presented to his physician with marked fatigue, nausea with occasional diarrhea, and a sore, swollen tongue. Lately he also has been experiencing a tingling feeling in his toes and a feeling of clumsiness. Microscopic examination of a blood sample indicated a reduced number of erythrocytes, many of which are megaloblasts, and a reduced number of leukocytes, including many large, hypersegmented cells. Hemoglobin and serum levels of vitamin B12 were below normal. Additional tests confirm pernicious anemia.
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Case Study: Cardiovascular System – Atherosclerosis
Question 1
Relate the pathophysiology of pernicious anemia to the manifestations listed above.
Answers may vary.
Question 2
Discuss how the gastric abnormalities contribute to vitamin B12 and iron deficiency and how vitamin B12 deficiency causes complications associated with pernicious anemia.
Answers may vary.
Question 3
Discuss other tests that could be performed to diagnose this type of anemia.
Answers may vary.
Question 4
Discuss the treatment available and the limitations.
Case Study
Cardiovascular System
Case Study: Cardiovascular System – Atherosclerosis
approx 30 min
Mr. Kelly is a 57-year-old man who consulted his physician after noticing marked leg pains while playing golf. He had previously noticed increasing fatigue and discomfort in his legs associated with moderate exercise. When sitting for extended periods with legs dangling, his legs became red, and sometimes his feet felt numb. His history indicates he smokes cigarettes and is chronically overweight. His blood cholesterol and other lipid levels are abnormal, and his physician suspects peripheral atherosclerosis as the cause of his discomfort.
Question 1
Discuss the development of atherosclerosis, including the predisposing factors in this case and the pathophysiological changes.
Answers may vary.
Question 2
Discuss the complications that might develop in this patient.
Answers may vary.
Case Study: Cardiovascular System – Atherosclerosis
Question 3
Discuss the treatments for all aspects of the patient’s condition, including slowing the progress of the atherosclerosis, maintaining circulation in the leg, and treating complications.
